After scoring 141 goals, Leonardo Jardim's team tops the French league and remains on course for the treble after reaching the Champions League semifinals on Wednesday, dispatching German side Borussia Dortmund 6-3 on aggregate.
Wednesday's second leg takes place at Monaco's Stade Louis II, with the Ligue 1 club aiming to reach a first Champions League semifinal since 2004, when they went on to lose in the final to Porto.
Barcelona had overcome a 4-0 first leg deficit against French club Paris Saint-Germain in the last-16 with a dramatic 6-1 win back on home soil.
The first of Monaco's 141 goals was scored by striker Radamel Falcao way back on July 27, against Turkish side Fenerbahce in the third qualifying round of the Champions League.
Monaco, whose next fixture is Sunday's league encounter with Lyon, are in the final four of the Champions League alongside Real Madrid, Atletico Madrid, and Juventus.
The Dortmund player who suffered a broken wrist in the attack on the team bus, Spanish defender Marc Bartra, was in the stands and received a Monaco shirt before the start of the match.
Three explosions rocked the Borussia coach on its way to the stadium in Germany last Tuesday, causing the match to be postponed for 24 hours. I can not expect everyone else to deal as I am, which is why we have to be very careful in how we criticise the players.
"Tonight it worked out fine and we qualified for the semi-finals". After every step we've taken we've looked at it and we've kept working. "We will give everything in both", added the coach.
But asked which side he feared the most, Jardim's answer spoke volumes for Monaco's confidence.
On the eve of the return leg, Tuchel told a press conference: 'We've got this out of our system now and we're more stable emotionally.
"That's what we know best so we're not going to do anything else".
The kick-off was delayed by five minutes but Dortmund's concentration was again affected.
Neymar had been Barca's hero in a remarkable finish with two goals and an assist in the final minutes against PSG in the previous round. We're ready and focused. "We will enjoy ourselves and draw on our qualities", said Jardim.
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